Possible role of glucose-6-phosphatase 3 in the pathogenesis of uterine leiomyomas
Background and aim: Glucose-6-phosphatase catalytic subunit 3 (G6PC3) has been recently described as a metabolite repair enzyme involved in the disposal of the phosphorylated glucose analog 1,5-anhydroglucitol-6-phosphate (1,5AG6P).This function is especially relevant in neutrophils; indeed, G6PC3 deficiency leads to neutropenia as the accumulated